The International Organization for Standardization (ISO) has officially approved cyclobunofen as the new common name for a novel carboxamide fungicide developed by Qingdao KingAgroot Chemical Compound Co., Ltd., marking a significant milestone for the Chinese agrochemical industry. The approval was confirmed on 10 December 2025, following the conclusion of the ISO consultation period with no objections received.
Cyclobunofen will be formally incorporated into the March 2026 update of the ISO 1750:2023 XML dataset, which catalogues internationally recognized common names for pesticides. This recognition provides the compound with global nomenclature consistency, facilitating regulatory submissions, scientific communication, and international trade.
Chemically, cyclobunofen is defined as a mixture of enantiomers, consisting of 80–100% N-[(1S,2S)-2-(2,4-dibromophenyl)cyclobutyl]-2-nitrobenzamide and 20–0% of the corresponding (1R,2R)-enantiomer. Its molecular formula is C₁₇H₁₄Br₂N₂O₃, and it is registered under CAS Reg. No. 3052252-62-4, with the major component assigned CAS No. 3038582-85-0. The compound belongs to the carboxamide class of fungicides, although its specific mode of action has not yet been publicly classified.
The Chinese common name for cyclobunofen is 硝苯菌酰胺, reflecting its nitrobenzamide structural features. Structurally, the molecule incorporates a dibromophenyl-substituted cyclobutyl moiety, a design that may offer novel biological performance and resistance management potential in crop protection.
The ISO approval of cyclobunofen underscores Qingdao KingAgroot’s growing capabilities in agrochemical innovation and intellectual property development. It also highlights China’s increasing contribution to the global pipeline of new active ingredients aimed at improving crop disease control and supporting sustainable agricultural productivity worldwide.
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